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Promoter-specific induction of the phosphatase SHP-1 by viral infection and cytokines in CNS glia

We have previously shown that the protein tyrosine phosphatase SHP-1 is highly expressed in CNS glia and is an important modulator of cytokine signaling. As such, mice genetically lacking SHP-1 display constitutive myelin abnormalities, severe virus-induced demyelinating disease, and defects in inna...

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Bibliografiske detaljer
Main Authors: Christophi, George P., Hudson, Chad A., Gruber, Ross, Chrisophi, Christoforos P., Massa, Paul T.
Format: Artigo
Sprog:Inglês
Udgivet: 2008
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3422745/
https://ncbi.nlm.nih.gov/pubmed/18331586
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1471-4159.2008.05337.x
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