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Induction of IL-33 expression and activity in central nervous system glia

IL-33 is a novel member of the IL-1 cytokine family and a potent inducer of type 2 immunity, as mast cells and Th2 CD4+ T cells respond to IL-33 with the induction of type 2 cytokines such as IL-13. IL-33 mRNA levels are extremely high in the CNS, and CNS glia possess both subunits of the IL-33R, ye...

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Main Authors: Hudson, Chad A., Christophi, George P., Gruber, Ross C., Wilmore, Joel R., Lawrence, David A., Massa, Paul T.
Formato: Artigo
Idioma:Inglês
Publicado em: The Society for Leukocyte Biology 2008
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2516894/
https://ncbi.nlm.nih.gov/pubmed/18552204
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1189/jlb.1207830
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