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New Insights for Drug Design from the X-Ray Crystallographic Structures of G-Protein-Coupled Receptors

Methodological advances in X-ray crystallography have made possible the recent solution of X-ray structures of pharmaceutically important G protein-coupled receptors (GPCRs), including receptors for biogenic amines, peptides, a nucleoside, and a sphingolipid. These high-resolution structures have gr...

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Autori principali: Jacobson, Kenneth A., Costanzi, Stefano
Natura: Artigo
Lingua:Inglês
Pubblicazione: The American Society for Pharmacology and Experimental Therapeutics 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3422707/
https://ncbi.nlm.nih.gov/pubmed/22695719
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/mol.112.079335
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