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Evaluation of Homology Modeling of G Protein-Coupled Receptors in Light of the A(2A) Adenosine Receptor Crystallographic Structure
Homology modeling of the human A(2A) adenosine receptor (AR) based on bovine rhodopsin predicted a protein structure that was very similar to the recently determined crystallographic structure. The inaccuracy of previous antagonist docking is related to the loop structure of rhodopsin being carried...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2720635/ https://ncbi.nlm.nih.gov/pubmed/19402631 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jm801533x |
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