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Cardiotonic Steroids Stabilize Regulator of G Protein Signaling 2 Protein Levels
Regulator of G protein signaling 2 (RGS2), a G(q)-specific GTPase-activating protein, is strongly implicated in cardiovascular function. RGS2(−/−) mice are hypertensive and prone to heart failure, and several rare human mutations that accelerate RGS2 degradation have been identified among patients w...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The American Society for Pharmacology and Experimental Therapeutics
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3422705/ https://ncbi.nlm.nih.gov/pubmed/22695717 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/mol.112.079293 |
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