High Expression of Nuclear Factor 90 (NF90) Leads to Mitochondrial Degradation in Skeletal and Cardiac Muscles

While NF90 has been known to participate in transcription, translation and microRNA biogenesis, physiological functions of this protein still remain unclear. To uncover this, we generated transgenic (Tg) mice using NF90 cDNA under the control of β-actin promoter. The NF90 Tg mice exhibited a reducti...

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Main Authors: Higuchi, Takuma, Sakamoto, Shuji, Kakinuma, Yoshihiko, Kai, Shoko, Yagyu, Ken-ichi, Todaka, Hiroshi, Chi, Eunsup, Okada, Shoshiro, Ujihara, Takako, Morisawa, Keiko, Ono, Masafumi, Sugiyama, Yasunori, Ishida, Waka, Fukushima, Atsuki, Tsuda, Masayuki, Agata, Yasutoshi, Taniguchi, Taketoshi
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2012
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3422296/
https://ncbi.nlm.nih.gov/pubmed/22912857
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0043340
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