Suppression of MicroRNA-7 (miR-7) Biogenesis by Nuclear Factor 90-Nuclear Factor 45 Complex (NF90-NF45) Controls Cell Proliferation in Hepatocellular Carcinoma

MicroRNA-7 (miR-7)has been characterized as an anti-oncogenic microRNA (miRNA) in several cancers, including hepatocellular carcinoma (HCC). However, the mechanism for the regulation of miR-7 production in tumors remains unclear. Here, we identified nuclear factor 90 (NF90) and NF45 complex (NF90-NF...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Higuchi, Takuma, Todaka, Hiroshi, Sugiyama, Yasunori, Ono, Masafumi, Tamaki, Nobuyuki, Hatano, Etsuro, Takezaki, Yuka, Hanazaki, Kazuhiro, Miwa, Takeshi, Lai, Sylvia, Morisawa, Keiko, Tsuda, Masayuki, Taniguchi, Taketoshi, Sakamoto, Shuji
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2016
Assuntos:
Molecular Bases of Disease
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5076517/
https://ncbi.nlm.nih.gov/pubmed/27519414
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.748210
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