High Expression of Nuclear Factor 90 (NF90) Leads to Mitochondrial Degradation in Skeletal and Cardiac Muscles

While NF90 has been known to participate in transcription, translation and microRNA biogenesis, physiological functions of this protein still remain unclear. To uncover this, we generated transgenic (Tg) mice using NF90 cDNA under the control of β-actin promoter. The NF90 Tg mice exhibited a reducti...

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Main Authors: Higuchi, Takuma, Sakamoto, Shuji, Kakinuma, Yoshihiko, Kai, Shoko, Yagyu, Ken-ichi, Todaka, Hiroshi, Chi, Eunsup, Okada, Shoshiro, Ujihara, Takako, Morisawa, Keiko, Ono, Masafumi, Sugiyama, Yasunori, Ishida, Waka, Fukushima, Atsuki, Tsuda, Masayuki, Agata, Yasutoshi, Taniguchi, Taketoshi
Format: Artigo
Language:Inglês
Published: Public Library of Science 2012
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3422296/
https://ncbi.nlm.nih.gov/pubmed/22912857
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0043340
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