Artemether resistance in vitro is linked to mutations in PfATP6 that also interact with mutations in PfMDR1 in travellers returning with Plasmodium falciparum infections

BACKGROUND: Monitoring resistance phenotypes for Plasmodium falciparum, using in vitro growth assays, and relating findings to parasite genotype has proved particularly challenging for the study of resistance to artemisinins. METHODS: Plasmodium falciparum isolates cultured from 28 returning travell...

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Main Authors: Pillai, Dylan R, Lau, Rachel, Khairnar, Krishna, Lepore, Rosalba, Via, Allegra, Staines, Henry M, Krishna, Sanjeev
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2012
Assuntos:
Research
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3422158/
https://ncbi.nlm.nih.gov/pubmed/22540925
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1475-2875-11-131
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