Artemether resistance in vitro is linked to mutations in PfATP6 that also interact with mutations in PfMDR1 in travellers returning with Plasmodium falciparum infections

BACKGROUND: Monitoring resistance phenotypes for Plasmodium falciparum, using in vitro growth assays, and relating findings to parasite genotype has proved particularly challenging for the study of resistance to artemisinins. METHODS: Plasmodium falciparum isolates cultured from 28 returning travell...

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Bibliografiske detaljer
Main Authors:	Pillai, Dylan R, Lau, Rachel, Khairnar, Krishna, Lepore, Rosalba, Via, Allegra, Staines, Henry M, Krishna, Sanjeev
Format:	Artigo
Sprog:	Inglês
Udgivet:	BioMed Central 2012
Fag:	Research
Online adgang:	https://ncbi.nlm.nih.gov/pmc/articles/PMC3422158/ https://ncbi.nlm.nih.gov/pubmed/22540925 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1475-2875-11-131
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Artemether resistance in vitro is linked to mutations in PfATP6 that also interact with mutations in PfMDR1 in travellers returning with Plasmodium falciparum infections

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