Sequential Evolution and Escape from Neutralization of Simian Immunodeficiency Virus SIVsmE660 Clones in Rhesus Macaques

Simian immunodeficiency virus (SIV) infection of rhesus macaques has become an important surrogate model for evaluating HIV vaccine strategies. The extreme resistance to neutralizing antibody (NAb) of many commonly used strains, such as SIVmac251/239 and SIVsmE543-3, limits their potential relevance...

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Главные авторы: Wu, Fan, Ourmanov, Ilnour, Kuwata, Takeo, Goeken, Robert, Brown, Charles R., Buckler-White, Alicia, Iyengar, Ranjini, Plishka, Ronald, Aoki, Scott T., Hirsch, Vanessa M.
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Microbiology 2012
Предметы:
Pathogenesis and Immunity
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3421745/
https://ncbi.nlm.nih.gov/pubmed/22696650
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00923-12
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