TRIM5α Restriction Affects Clinical Outcome and Disease Progression in Simian Immunodeficiency Virus-Infected Rhesus Macaques

Tripartite motif-containing protein 5α (TRIM5α) is considered to be a potential target for cell-based gene modification therapy against human immunodeficiency virus type 1 (HIV-1) infection. In the present study, we used a relevant rhesus macaque model of infection with simian immunodeficiency virus...

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Bibliographische Detailangaben
Veröffentlicht in:J Virol
Hauptverfasser: Wu, Fan, Ourmanov, Ilnour, Riddick, Nadeene, Matsuda, Kenta, Whitted, Sonya, Plishka, Ronald J., Buckler-White, Alicia, Starost, Matthew F., Hirsch, Vanessa M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2014
Schlagworte:
Pathogenesis and Immunity
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4338887/
https://ncbi.nlm.nih.gov/pubmed/25473059
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02978-14
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