TRIM5α Resistance Escape Mutations in the Capsid Are Transferable between Simian Immunodeficiency Virus Strains

TRIM5α polymorphism limits and complicates the use of simian immunodeficiency virus (SIV) for evaluation of human immunodeficiency virus (HIV) vaccine strategies in rhesus macaques. We previously reported that the TRIM5α-sensitive SIV from sooty mangabeys (SIVsm) clone SIVsmE543-3 acquired amino aci...

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Bibliografiska uppgifter
I publikationen:J Virol
Huvudupphovsmän: Wu, Fan, Kirmaier, Andrea, White, Ellen, Ourmanov, Ilnour, Whitted, Sonya, Matsuda, Kenta, Riddick, Nadeene, Hall, Laura R., Morgan, Jennifer S., Plishka, Ronald J., Buckler-White, Alicia, Johnson, Welkin E., Hirsch, Vanessa M.
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Microbiology 2016
Ämnen:
Pathogenesis and Immunity
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5126367/
https://ncbi.nlm.nih.gov/pubmed/27681142
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01620-16
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