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Solution Structure, Conformational Dynamics, and CD4-Induced Activation in Full-Length, Glycosylated, Monomeric HIV gp120

The gp120 subunit of the HIV Env glycoprotein is responsible for receptor interactions leading to viral entry and is a primary target for neutralizing antibodies. Most structural studies have focused on the heavily truncated, deglycosylated gp120 core, leaving fundamental aspects of the glycoprotein...

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Autori principali: Guttman, Miklos, Kahn, Maria, Garcia, Natalie K., Hu, Shiu-Lok, Lee, Kelly K.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3421722/
https://ncbi.nlm.nih.gov/pubmed/22674993
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.07224-11
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