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Binding of Full-Length HIV-1 gp120 to CD4 Induces Structural Reorientation around the gp120 Core

Small-angle x-ray scattering data on the unliganded full-length fully glycosylated HIV-1 gp120, the soluble CD4 (domains 1–2) receptor, and their complex in solution are presented. Ab initio structure restorations using these data provides the first look at the envelope shape for the unliganded and...

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Detalhes bibliográficos
Main Authors: Ashish, Garg, Renu, Anguita, Juan, Krueger, Joanna K.
Formato: Artigo
Idioma:Inglês
Publicado em: Biophysical Society 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1557575/
https://ncbi.nlm.nih.gov/pubmed/16844755
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.106.090381
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