Autophagic activity dictates the cellular response to oncogenic RAS

RAS is frequently mutated in human cancers and has opposing effects on autophagy and tumorigenesis. Identifying determinants of the cellular responses to RAS is therefore vital in cancer research. Here, we show that autophagic activity dictates the cellular response to oncogenic RAS. N-terminal Apop...

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Bibliographische Detailangaben
Hauptverfasser: Wang, Yihua, Wang, Xiao Dan, Lapi, Eleonora, Sullivan, Alexandra, Jia, Wei, He, You-Wen, Ratnayaka, Indrika, Zhong, Shan, Goldin, Robert D., Goemans, Christoph G., Tolkovsky, Aviva M., Lu, Xin
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2012
Schlagworte:
Biological Sciences
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3421174/
https://ncbi.nlm.nih.gov/pubmed/22847423
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1120193109
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