Autophagic activity dictates the cellular response to oncogenic RAS

RAS is frequently mutated in human cancers and has opposing effects on autophagy and tumorigenesis. Identifying determinants of the cellular responses to RAS is therefore vital in cancer research. Here, we show that autophagic activity dictates the cellular response to oncogenic RAS. N-terminal Apop...

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Detalhes bibliográficos
Main Authors: Wang, Yihua, Wang, Xiao Dan, Lapi, Eleonora, Sullivan, Alexandra, Jia, Wei, He, You-Wen, Ratnayaka, Indrika, Zhong, Shan, Goldin, Robert D., Goemans, Christoph G., Tolkovsky, Aviva M., Lu, Xin
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2012
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3421174/
https://ncbi.nlm.nih.gov/pubmed/22847423
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1120193109
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