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GRP78/BiP is a Novel Downstream Target of IGF-1 Receptor Mediated Signaling

Glucose regulated protein 78/immunoglobulin binding protein (GRP78/BiP) is an ER chaperone protein and master regulator of the unfolded protein response (UPR). The response of GRP78 to overt pharmacologically induced ER stress is well established, whereas the modulation of GRP78 to physiologic chang...

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Autors principals: PFAFFENBACH, KYLE T., PONG, MICHELLE, MORGAN, TODD E., WANG, HONGJUN, OTT, KATE, ZHOU, BEIYUN, LONGO, VALTER D., LEE, AMY S.
Format: Artigo
Idioma:Inglês
Publicat: 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3421054/
https://ncbi.nlm.nih.gov/pubmed/22422508
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcp.24090
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