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Soluble guanylyl cyclase requires heat shock protein 90 for heme insertion during maturation of the NO-active enzyme

Heme insertion is key during maturation of soluble guanylyl cyclase (sGC) because it enables sGC to recognize NO and transduce its multiple biological effects. Although sGC is often associated with the 90-kDa heat shock protein (hsp90) in cells, the implications are unclear. The present study reveal...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Ghosh, Arnab, Stuehr, Dennis J.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: National Academy of Sciences 2012
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3420196/
https://ncbi.nlm.nih.gov/pubmed/22837396
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1205854109
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