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Soluble guanylyl cyclase requires heat shock protein 90 for heme insertion during maturation of the NO-active enzyme
Heme insertion is key during maturation of soluble guanylyl cyclase (sGC) because it enables sGC to recognize NO and transduce its multiple biological effects. Although sGC is often associated with the 90-kDa heat shock protein (hsp90) in cells, the implications are unclear. The present study reveal...
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| Glavni autori: | , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
National Academy of Sciences
2012
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3420196/ https://ncbi.nlm.nih.gov/pubmed/22837396 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1205854109 |
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