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Effective inhibition of cytomegalovirus infection by external guide sequences in mice

Ribonuclease P complexed with external guide sequence (EGS) bound to mRNA represents a unique nucleic acid-based gene interference approach for modulation of gene expression. Compared with other strategies, such as RNA interference, the EGS-based technology is unique because a custom-designed EGS mo...

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Autores principales: Jiang, Xiaohong, Gong, Hao, Chen, Yuan-Chuan, Vu, Gia-Phong, Trang, Phong, Zhang, Chen-Yu, Lu, Sangwei, Liu, Fenyong
Formato: Artigo
Lenguaje:Inglês
Publicado: National Academy of Sciences 2012
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3420183/
https://ncbi.nlm.nih.gov/pubmed/22826233
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1201620109
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