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Hydrophobic gating of mechanosensitive channel of large conductance evidenced by single-subunit resolution

Mechanosensitive (MS) ion channels are membrane proteins that detect and respond to membrane tension in all branches of life. In bacteria, MS channels prevent cells from lysing upon sudden hypoosmotic shock by opening and releasing solutes and water. Despite the importance of MS channels and ongoing...

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Detalhes bibliográficos
Main Authors: Birkner, Jan Peter, Poolman, Bert, Koçer, Armağan
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3420157/
https://ncbi.nlm.nih.gov/pubmed/22826215
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1205270109
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