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Energetic and Spatial Parameters for Gating of the Bacterial Large Conductance Mechanosensitive Channel, MscL

MscL is multimeric protein that forms a large conductance mechanosensitive channel in the inner membrane of Escherichia coli. Since MscL is gated by tension transmitted through the lipid bilayer, we have been able to measure its gating parameters as a function of absolute tension. Using purified Msc...

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Bibliographic Details
Main Authors: Sukharev, Sergei I., Sigurdson, Wade J., Kung, Ching, Sachs, Frederick
Format: Artigo
Language:Inglês
Published: The Rockefeller University Press 1999
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2217166/
https://ncbi.nlm.nih.gov/pubmed/10102934
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