A Novel Carbamoyloxy Arylalkanoyl Arylpiperazine Compound (SKL-NP) Inhibits Hyperpolarization-Activated Cyclic Nucleotide-Gated (HCN) Channel Currents in Rat Dorsal Root Ganglion Neurons

In this study, we determined mode of action of a novel carbamoyloxy arylalkanoyl arylpiperazine compound (SKL-NP) on hyperpolarization-activated cyclic nucleotide-gated (HCN) channel currents (I(h)) that plays important roles in neuropathic pain. In small or medium-sized dorsal root ganglion (DRG) n...

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Bibliografske podrobnosti
Main Authors: Chung, Gehoon, Kim, Tae-hyung, Shin, Hyewon, Chae, Eunhee, Yi, Hanju, Moon, Hongsik, Kim, Hyun Jin, Kim, Joong Soo, Jung, Sung Jun, Oh, Seog Bae
Format: Artigo
Jezik:Inglês
Izdano: The Korean Physiological Society and The Korean Society of Pharmacology 2012
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Original Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3419758/
https://ncbi.nlm.nih.gov/pubmed/22915988
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4196/kjpp.2012.16.4.237
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