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ENABLING CLINICAL CANCER GENOMICS FOR RARE MUTATIONS: COLD-PCR MAGNIFIES MUTATIONS PRIOR TO TARGETED AMPLICON RE-SEQUENCING
Despite widespread interest in the application of next-generation-sequencing (NGS) to the mutation profiling of individual cancer specimens, the onset of personalized clinical genomics is currently stalled due in part to technical hurdles. As tumors are genetically-heterogeneous and often mixed with...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3418918/ https://ncbi.nlm.nih.gov/pubmed/22194627 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1373/clinchem.2011.176198 |
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