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Pharmacological inhibition of βIIPKC is cardioprotective in late-stage hypertrophy

We previously found that in the hearts of hypertensive Dahl salt-sensitive rats, βIIPKC levels increase during the transition from compensated cardiac hypertrophy to cardiac dysfunction. Here we showed that a six-week treatment of these hypertensive rats with a βIIPKC-specific inhibitor, βIIV5-3, pr...

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Detalhes bibliográficos
Main Authors: Ferreira, Julio C.B., Koyanagi, Tomoyoshi, Palaniyandi, Suresh S., Fajardo, Giovanni, Churchill, Eric N., Budas, Grant, Disatnik, Marie-Helene, Bernstein, Daniel, Brum, Patricia C., Mochly-Rosen, Daria
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3418885/
https://ncbi.nlm.nih.gov/pubmed/21920368
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yjmcc.2011.08.025
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