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Protein Thiyl Radical Mediates S-glutathionylation of Complex I
Complex I is a critical site of O(2)(•−) production and the major host of reactive protein thiols in mitochondria. In response to oxidative stress, Complex I protein thiols at the 51 kDa and 75 kDa subunits are reversibly S-glutathionylated. The mechanism of Complex I S-glutathionylation is mainly o...
Tallennettuna:
| Päätekijät: | , , , , |
|---|---|
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
2012
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3418477/ https://ncbi.nlm.nih.gov/pubmed/22634394 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.freeradbiomed.2012.05.025 |
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