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Protein Thiyl Radical Mediates S-glutathionylation of Complex I
Complex I is a critical site of O(2)(•−) production and the major host of reactive protein thiols in mitochondria. In response to oxidative stress, Complex I protein thiols at the 51 kDa and 75 kDa subunits are reversibly S-glutathionylated. The mechanism of Complex I S-glutathionylation is mainly o...
में बचाया:
| मुख्य लेखकों: | , , , , |
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| स्वरूप: | Artigo |
| भाषा: | Inglês |
| प्रकाशित: |
2012
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| विषय: | |
| ऑनलाइन पहुंच: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3418477/ https://ncbi.nlm.nih.gov/pubmed/22634394 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.freeradbiomed.2012.05.025 |
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