The unstructured linker arms of Mlh1-Pms1 are important for interactions with DNA during mismatch repair

DNA mismatch repair (MMR) models have proposed that MSH proteins identify DNA polymerase errors while interacting with the DNA replication fork. MLH proteins (primarily Mlh1-Pms1 in baker’s yeast) then survey the genome for lesion-bound MSH proteins. The resulting MSH-MLH complex formed at a DNA les...

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Bibliographische Detailangaben
Hauptverfasser: Plys, Aaron J., Rogacheva, Maria V., Greene, Eric C., Alani, Eric
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2012
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3418407/
https://ncbi.nlm.nih.gov/pubmed/22659005
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2012.05.030
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