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Correction of a carboxyl terminal simian immunodeficiency virus Nef frameshift mutation restores virus replication in macaques

Previous studies demonstrated that the nef gene is a critical determinant of the pathogenicity of simian immunodeficiency virus (SIV) in macaques. In the present study, we evaluated the effect of a spontaneous frameshift mutation in the C-terminus of the nef gene of the minimally pathogenic SIVsmH4i...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Zheng, Yanfang, Ourmanov, Ilnour, Goeken, Robert M., Whitted, Sonya, Brown, Charles R., Buckler-White, Alicia, Iyengar, Ranjini, Plishka, Ronald J., Hirsch, Vanessa M.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2010
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3418331/
https://ncbi.nlm.nih.gov/pubmed/20303562
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2010.02.026
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