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Correction of a carboxyl terminal simian immunodeficiency virus Nef frameshift mutation restores virus replication in macaques
Previous studies demonstrated that the nef gene is a critical determinant of the pathogenicity of simian immunodeficiency virus (SIV) in macaques. In the present study, we evaluated the effect of a spontaneous frameshift mutation in the C-terminus of the nef gene of the minimally pathogenic SIVsmH4i...
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| Main Authors: | , , , , , , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
2010
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3418331/ https://ncbi.nlm.nih.gov/pubmed/20303562 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2010.02.026 |
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