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Reduction of the [2Fe-2S] Cluster Accompanies Formation of the Intermediate 9-Mercaptodethiobiotin in Escherichia coli Biotin Synthase()

Biotin synthase catalyzes the conversion of dethiobiotin (DTB) to biotin through the oxidative addition of sulfur between two saturated carbon atoms, generating a thiophane ring fused to the existing ureido ring. Biotin synthase is a member of the Radical SAM superfamily, composed of enzymes that re...

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書誌詳細
主要な著者: Taylor, Andrew M., Stoll, Stefan, Britt, R. David, Jarrett, Joseph T.
フォーマット: Artigo
言語:Inglês
出版事項: 2011
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3418055/
https://ncbi.nlm.nih.gov/pubmed/21859080
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi201042r
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