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Spectroscopic Changes during a Single Turnover of Biotin Synthase: Destruction of a [2Fe-2S] Cluster Accompanies Sulfur Insertion()

Biotin synthase catalyzes the insertion of a sulfur atom between the saturated C6 and C9 carbons of dethiobiotin. Catalysis requires AdoMet and flavodoxin and generates 5′-deoxyadenosine and methionine, suggesting that biotin synthase is an AdoMet-dependent radical enzyme. Biotin synthase (BioB) is...

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Bibliografske podrobnosti
Main Authors: Ugulava, Natalia B., Sacanell, Carlos J., Jarrett, Joseph T.
Format: Artigo
Jezik:Inglês
Izdano: 2001
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC1489075/
https://ncbi.nlm.nih.gov/pubmed/11444982
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