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HIV-1 Nef Protein Is Secreted into Vesicles That Can Fuse with Target Cells and Virions

HIV-1 Nef is a major determinant in HIV-1 pathogenicity. However, its properties have mainly been associated with its biochemical activities within the producer cell. Nef is also secreted from infected and transfected cells. Our primary objective was to determine the nature of secreted Nef protein a...

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Autori principali: Campbell, Tamika D., Khan, Mahfuz, Huang, Ming-Bo, Bond, Vincent Craig, Powell, Michael D.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2008
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3418053/
https://ncbi.nlm.nih.gov/pubmed/18646314
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