Chimeric Human Immunodeficiency Virus Type 1 (HIV-1) Virions Containing HIV-2 or Simian Immunodeficiency Virus Nef Are Resistant to Cyclosporine Treatment

The viral protein Nef and the cellular factor cyclophilin A are both required for full infectivity of human immunodeficiency virus type 1 (HIV-1) virions. In contrast, HIV-2 and simian immunodeficiency virus (SIV) do not incorporate cyclophilin A into virions or need it for full infectivity. Since N...

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Detalhes bibliográficos
Main Authors: Khan, Mahfuz, Jin, Lingling, Huang, Ming Bo, Miles, Lesa, Bond, Vincent C., Powell, Michael D.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2004
Assuntos:
Replication
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC369439/
https://ncbi.nlm.nih.gov/pubmed/14747548
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.78.4.1843-1850.2004
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