Increasing TNF Levels Solely in the Rat Hippocampus Produces Persistent Pain-like Symptoms

The manifestation of chronic, neuropathic pain includes elevated levels of the cytokine tumor necrosis factor-alpha (TNF). Previously, we have shown that the hippocampus, an area of the brain most notable for its role in learning and memory formation, plays a fundamental role in pain sensation. Usin...

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Autori principali: Martuscello, Regina T., Spengler, Robert N., Bonoiu, Adela C., Davidson, Bruce A., Helinski, Jadwiga, Ding, Hong, Mahajan, Supriya, Kumar, Rajiv, Bergey, Earl J., Knight, Paul R., Prasad, Paras N., Ignatowski, Tracey A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2012
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3417838/
https://ncbi.nlm.nih.gov/pubmed/22770843
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.pain.2012.05.028
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