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Antinociception mediated by alpha(2)-adrenergic activation involves increasing TNFα expression and restoring TNFα and alpha(2)-adrenergic inhibition of norepinephrine release

The central component that establishes chronic pain from peripheral nerve injury is associated with increased tumor necrosis factor-α (TNFα) production in the brain. This study examined TNFα and its reciprocally permissive role with α(2)-adrenergic activation during peak and progressive decline of t...

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Bibliografske podrobnosti
Main Authors: Spengler, Robert N., Sud, Reeteka, Knight, Paul R., Ignatowski, Tracey A.
Format: Artigo
Jezik:Inglês
Izdano: 2006
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC1839855/
https://ncbi.nlm.nih.gov/pubmed/17055005
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuropharm.2006.08.027
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