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Antinociception mediated by alpha(2)-adrenergic activation involves increasing TNFα expression and restoring TNFα and alpha(2)-adrenergic inhibition of norepinephrine release
The central component that establishes chronic pain from peripheral nerve injury is associated with increased tumor necrosis factor-α (TNFα) production in the brain. This study examined TNFα and its reciprocally permissive role with α(2)-adrenergic activation during peak and progressive decline of t...
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| Auteurs principaux: | , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2006
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1839855/ https://ncbi.nlm.nih.gov/pubmed/17055005 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuropharm.2006.08.027 |
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