Beta-Adrenergic Receptor 1 Selective Antagonism Inhibits Norepinephrine-Mediated TNF-Alpha Downregulation in Experimental Liver Cirrhosis

BACKGROUND: Bacterial translocation is a frequent event in cirrhosis leading to an increased inflammatory response. Splanchnic adrenergic system hyperactivation has been related with increased bacterial translocation. We aim at evaluating the interacting mechanism between hepatic norepinephrine and...

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Main Authors: Zapater, Pedro, Gómez-Hurtado, Isabel, Peiró, Gloria, González-Navajas, José Manuel, García, Irma, Giménez, Paula, Moratalla, Alba, Such, José, Francés, Rubén
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3423372/
https://ncbi.nlm.nih.gov/pubmed/22916250
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0043371
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