The potential of GPNMB as novel neuroprotective factor in amyotrophic lateral sclerosis

Amyotrophic lateral sclerosis (ALS) is an incurable and fatal neurodegenerative disease characterized by the loss of motor neurons. Despite substantial research, the causes of ALS remain unclear. Glycoprotein nonmetastatic melanoma protein B (GPNMB) was identified as an ALS-related factor using DNA...

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Main Authors: Tanaka, Hirotaka, Shimazawa, Masamitsu, Kimura, Masataka, Takata, Masafumi, Tsuruma, Kazuhiro, Yamada, Mitsunori, Takahashi, Hitoshi, Hozumi, Isao, Niwa, Jun-ichi, Iguchi, Yohei, Nikawa, Takeshi, Sobue, Gen, Inuzuka, Takashi, Hara, Hideaki
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2012
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3417778/
https://ncbi.nlm.nih.gov/pubmed/22891158
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep00573
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