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Glycoprotein nonmetastatic melanoma protein B extracellular fragment shows neuroprotective effects and activates the PI3K/Akt and MEK/ERK pathways via the Na(+)/K(+)-ATPase

Glycoprotein nonmetastatic melanoma protein B (GPNMB) plays important roles in various types of cancer and amyotrophic lateral sclerosis (ALS). The details of GPNMB function and its interacting protein have not been clarified. Therefore, to identify GPNMB binding partners on the cell membrane, we us...

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Bibliografiske detaljer
Udgivet i:Sci Rep
Main Authors: Ono, Yoko, Tsuruma, Kazuhiro, Takata, Masafumi, Shimazawa, Masamitsu, Hara, Hideaki
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4796790/
https://ncbi.nlm.nih.gov/pubmed/26988030
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep23241
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