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Glycoprotein nonmetastatic melanoma protein B extracellular fragment shows neuroprotective effects and activates the PI3K/Akt and MEK/ERK pathways via the Na(+)/K(+)-ATPase

Glycoprotein nonmetastatic melanoma protein B (GPNMB) plays important roles in various types of cancer and amyotrophic lateral sclerosis (ALS). The details of GPNMB function and its interacting protein have not been clarified. Therefore, to identify GPNMB binding partners on the cell membrane, we us...

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Bibliografische gegevens
Gepubliceerd in:Sci Rep
Hoofdauteurs: Ono, Yoko, Tsuruma, Kazuhiro, Takata, Masafumi, Shimazawa, Masamitsu, Hara, Hideaki
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Nature Publishing Group 2016
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4796790/
https://ncbi.nlm.nih.gov/pubmed/26988030
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep23241
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