Apoptosis‐Inducing Factor and Cyclophilin A Cotranslocate to the Motor Neuronal Nuclei in Amyotrophic Lateral Sclerosis Model Mice

Aims: Amyotrophic lateral sclerosis (ALS) is a fatal motor neuron disease whose mechanism is not understood. Recently, it was reported that apoptosis‐inducing factor (AIF) was involved in motor neuronal cell death in ALS model mice, and AIF‐induced neuronal cell death by interacting with cyclophilin...

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Detalhes bibliográficos
Publicado no:CNS Neurosci Ther
Main Authors: Tanaka, Hirotaka, Shimazaki, Hiroki, Kimura, Masataka, Izuta, Hiroshi, Tsuruma, Kazuhiro, Shimazawa, Masamitsu, Hara, Hideaki
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 2010
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6493854/
https://ncbi.nlm.nih.gov/pubmed/20553309
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1755-5949.2010.00180.x
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