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Divergent Behavior of Glycosylated Threonine and Serine Derivatives in Solid Phase Peptide Synthesis

[Image: see text] Solid phase peptide coupling of glycosylated threonine derivatives was systematically evaluated. In contrast to glycosylated serine derivatives which are highly prone to epimerization, glycosylated threonine derivatives produce only negligible amounts of epimerization. Under forcin...

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Detalhes bibliográficos
Main Authors: Zhang, Yalong, Muthana, Saddam M., Barchi, Joseph J., Gildersleeve, Jeffrey C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3417326/
https://ncbi.nlm.nih.gov/pubmed/22817697
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ol301723e
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