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Enhanced Epimerization of Glycosylated Amino Acids During Solid Phase Peptide Synthesis

Glycopeptides are extremely useful for basic research and clinical applications, but access to structurally-defined glycopeptides is limited by the difficulties in synthesizing this class of compounds. In this study, we demonstrate that many common peptide coupling conditions used to prepare O-linke...

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Detalhes bibliográficos
Main Authors: Zhang, Yalong, Muthana, Saddam M., Farnsworth, David, Ludek, Olaf, Adams, Kristie, Barchi, Joseph J., Gildersleeve, Jeffrey C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3324660/
https://ncbi.nlm.nih.gov/pubmed/22390544
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja212188r
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