Comparative Genomic Analysis of Primary Versus Metastatic Colorectal Carcinomas

PURPOSE: To compare the mutational and copy number profiles of primary and metastatic colorectal carcinomas (CRCs) using both unpaired and paired samples derived from primary and metastatic disease sites. PATIENTS AND METHODS: We performed a multiplatform genomic analysis of 736 fresh frozen CRC tum...

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Autori principali: Vakiani, Efsevia, Janakiraman, Manickam, Shen, Ronglai, Sinha, Rileen, Zeng, Zhaoshi, Shia, Jinru, Cercek, Andrea, Kemeny, Nancy, D'Angelica, Michael, Viale, Agnes, Heguy, Adriana, Paty, Philip, Chan, Timothy A., Saltz, Leonard B., Weiser, Martin, Solit, David B.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society of Clinical Oncology 2012
Soggetti:
Original Reports
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3417049/
https://ncbi.nlm.nih.gov/pubmed/22665543
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1200/JCO.2011.38.2994
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