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Partial Escape of HIV-1 from Cytotoxic T Lymphocytes during Chronic Infection
Viral mutational escape from CD8(+) cytotoxic T lymphocytes (CTLs) is typically considered to be a dichotomous process and uncommon during chronic HIV-1 infection. Ex vivo passaging of HIV-1 from persons with chronic infection, however, revealed the evolution of many fixed substitutions within and a...
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| Autores principales: | , , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
American Society for Microbiology
2012
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3416319/ https://ncbi.nlm.nih.gov/pubmed/22553321 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.06724-11 |
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