Lineage-Specific Differences between Human and Simian Immunodeficiency Virus Regulation of gp120 Trimer Association and CD4 Binding

Metastable conformations of the gp120 and gp41 envelope glycoproteins of human immunodeficiency virus type 1 (HIV-1) and simian immunodeficiency virus (SIV) must be maintained in the unliganded state of the envelope glycoprotein trimer. Binding of gp120 to the primary receptor, CD4, triggers the tra...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Finzi, Andrés, Pacheco, Beatriz, Xiang, Shi-Hua, Pancera, Marie, Herschhorn, Alon, Wang, Liping, Zeng, Xing, Desormeaux, Anik, Kwong, Peter D., Sodroski, Joseph
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2012
Assuntos:
Genetic Diversity and Evolution
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3416166/
https://ncbi.nlm.nih.gov/pubmed/22696649
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01076-12
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados