A novel fumarate hydratase-deficient HLRCC kidney cancer cell line, UOK268: a model of the Warburg effect in cancer

The role of energy deregulation and altered/adapted metabolism in tumor cells is an increasing important issue in understanding cancer. Hereditary leiomyomatosis renal cell carcinoma (HLRCC) is an aggressive form of RCC characterized by germline mutation of fumarate hydratase (FH) followed by somati...

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Autori principali: Yang, Youfeng, Valera, Vladimir, Sourbier, Carol, Vocke, Cathy D., Wei, Minghui, Pike, Lisa, Huang, Ying, Merino, Maria A., Bratslavsky, Gennady, Wu, Min, Ricketts, Christopher J, Linehan, W. Marston
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3415708/
https://ncbi.nlm.nih.gov/pubmed/22867999
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cancergen.2012.05.001
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