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A novel fumarate hydratase-deficient HLRCC kidney cancer cell line, UOK268: a model of the Warburg effect in cancer
The role of energy deregulation and altered/adapted metabolism in tumor cells is an increasing important issue in understanding cancer. Hereditary leiomyomatosis renal cell carcinoma (HLRCC) is an aggressive form of RCC characterized by germline mutation of fumarate hydratase (FH) followed by somati...
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| Main Authors: | , , , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3415708/ https://ncbi.nlm.nih.gov/pubmed/22867999 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cancergen.2012.05.001 |
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