A novel fumarate hydratase-deficient HLRCC kidney cancer cell line, UOK268: a model of the Warburg effect in cancer

The role of energy deregulation and altered/adapted metabolism in tumor cells is an increasing important issue in understanding cancer. Hereditary leiomyomatosis renal cell carcinoma (HLRCC) is an aggressive form of RCC characterized by germline mutation of fumarate hydratase (FH) followed by somati...

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Bibliografiske detaljer
Main Authors: Yang, Youfeng, Valera, Vladimir, Sourbier, Carol, Vocke, Cathy D., Wei, Minghui, Pike, Lisa, Huang, Ying, Merino, Maria A., Bratslavsky, Gennady, Wu, Min, Ricketts, Christopher J, Linehan, W. Marston
Format: Artigo
Sprog:Inglês
Udgivet: 2012
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3415708/
https://ncbi.nlm.nih.gov/pubmed/22867999
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cancergen.2012.05.001
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