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Catalytic Asymmetric Synthesis of Secondary Nitriles via Stereoconvergent Negishi Arylations and Alkenylations of Racemic α-Bromonitriles

The first method for the stereoconvergent cross-coupling of racemic α-halonitriles is described, specifically, nickel-catalyzed Negishi arylations and alkenylations that furnish an array of enantioenriched α-arylnitriles and allylic nitriles, respectively. Noteworthy features of this investigation i...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Choi, Junwon, Fu, Gregory C.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3415582/
https://ncbi.nlm.nih.gov/pubmed/22612264
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja303442q
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